Molecular modeling (Computer aided drug design). 1
Drug receptor interaction: force involved. 1
Steric features of drugs. 2
Optical isomerism and biological activity. 1
Calculated conformation. 1
Three- dimensional quantitative structure activity relationships and databases.1
Isosterism. 1
Drug-receptor interaction and subsequent events. 1
General pathways of drug metabolism: Sites of drug biotransformation; Role of cytochrome P450 mono-oxygenases in oxidative biotransformation; Oxidative reactions; Reductive reactions; Hydrolytic reactions; Phase II reactions. 22
Factors affecting drug metabolism. 2
Title of the course: Pharmacology I
Level: 3rd Class, 2nd Semester
Credit hours/week: Theory 3
Reference text: Lipincott Pharmacology 3rd Edition, Latest edition
Objectives: To introduce pharmacy students to the basis of general pharmacology.
The student will learn about various body systems and drugs used to affect them in health and disease. Moreover the course will cover the drugs used to treat microbial infections.
Pharmacology I
General introduction to Pharmacology. 2
Pharmacokinetics. 4
Drug Receptor interaction and Pharmacodynamics.4
The autonomic nervous system (ANS).
Cholinergic system. 6
Adrenergic system. 6
Principal of antimicrobial therapy. 2
β- lactam and other cell wall synthesis inhibitor antibiotics 4
Protien synthesis inhibitors 4
Quinolones, Folate antagonists, and urinary tract antiseptics. 3
Antimycobacterium drugs 2
Antifungal drugs. 2
Antiprotozoal drugs. 1
Anthelmintic drugs. 2
Antiviral drugs. 1
Title of the course: Pharmaceutical Technology II
Level: 3rd Class, 2nd Semester
Credit hours/week: Theory 3 Practical 2 (4 credit units)
Reference text: Pharmaceutical Dosage forms and Drug Delivery Systems By Haward A. Ansel; latest edition. and Sprowel’s American Pharmacy.
Objectives: To teach theoretical bases for the technology of preparing different dosage forms with respect to their raw materials, compositions, methods of preparation, stability, storage and uses; in addition to define and characterize the possible incompatibilities that may occur in dosage forms.
Pharmaceutical Technology II
Emulsions; purpose of emulsification; methods of emulsification; emulsifying agents; HLB system; stability of emulsions.10
Lotions; liniments and collodions. 5
Suppositories. 6
Powdered dosage forms. 10
Semisolid dosage forms. 10